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NANDROLONE PHARMACY
Anabolic Steroids. Compared to testosterone, it has a higher, long-term anabolic activity (3-4 weeks - when using the decanoate ester) and low androgenic activity. It causes the activation of regulatory genes in the cell nucleus by binding to specific receptor proteins on the cell surface of the target organ and the formation of a receptor-nandrolone complex, which ensures the transport of the latter across the cell membrane into the hyaloplasm. from where it penetrates through the nuclear membrane into the cell nucleus.
The androgenic action consists in stimulating the synthesis of nucleic acids (DNA, RNA) and structural proteins (which is associated with an increase in the absorption of nitrogen, phosphorus, sulfur and K in the body), Buy Nandrolone in Britain, increased tissue respiration and oxidative phosphorylation in skeletal muscles with accumulation of macroerg (ATP, creatine phosphate) ... Promotes the fixation of Ca2 in the bones, an increase in bone mass in osteoporosis, an increase in appetite, an increase muscle mass with a corresponding increase in body weight.
It accelerates the growth of male genital organs and the formation of secondary sexual characteristics in the male model. Stimulates the secretory activity of androgen-dependent glands - male reproductive (activation of the process of spermatogenesis), sebaceous; at high doses, it causes suppression of Leydig cells and reduces the synthesis of endogenous sex hormones by inhibiting the production of FSH and LH by the pituitary gland (negative feedback).
The anabolic effect is manifested by the activation of reparative processes in the epithelium (integumentary and glandular), in the bone and muscle tissues following the stimulation of protein synthesis and structural components of the cells. Increases the absorption of amino acids from the small intestine (against the background of a high-protein diet), creating a positive nitrogen balance.
It stimulates the production of erythropoietin and activates anabolic processes in the bone marrow which, with the simultaneous administration of Fe preparations, manifests itself as an anti-anemic effect. Violates the synthesis of vitamin K-dependent plasma coagulation factors (II, V, VII, X) in the liver, modifies the plasma lipid profile (increases the concentration of LDL and decreases the HDL), improves the reabsorption of Na and water in the kidneys, contributing to the formation of peripheral edema. Effective in women with disseminated breast cancer.